The recent outbreak of COVID-19 has motivated researchers to contribute in the area of medical imaging using artificial intelligence and deep learning. Super-resolution (SR), in the past few years, has produced remarkable results using deep learning methods. The ability of deep learning methods to learn the non-linear mapping from low-resolution (LR) images to their corresponding high-resolution (HR) images leads to compelling results for SR in diverse areas of research. In this paper, we propose a deep learning based image super-resolution architecture in Tchebichef transform domain. This is achieved by integrating a transform layer into the proposed architecture through a customized Tchebichef convolutional layer (TCL).